Pyruvate Kinase
Ordering Recommendation
Preferred initial screening test for pyruvate kinase deficiency.
New York DOH Approval Status
Specimen Required
Lavender (EDTA) or Pink (K2EDTA). Also acceptable: Green (Sodium or Lithium Heparin) or Yellow (ACD Solution A or B).
Do not freeze. Transport 1 mL whole blood. (Min: 0.5 mL)
Refrigerated.
Ambient: Unacceptable; Refrigerated: 20 days; Frozen: Unacceptable
Methodology
Quantitative Enzymatic Assay
Performed
Sun-Sat
Reported
1-2 days
Reference Interval
4.6-11.2 U/g Hb
Interpretive Data
Standard
Note
Patients who have recently received transfusions have normal donor cells that may mask PK deficient erythrocytes.
Hotline History
CPT Codes
84220
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
0080290 | Pyruvate Kinase | 32552-2 |
Aliases
- PK
- Pyruvate Kinase (RBC)